Abstract
Breast cancer, worldwide, represents the first cause of death for malignant neoplasms, involving 14% of deaths because of cancer in women. The more frequent types are infiltrating ductal carcinoma representing 75%, and infiltrating lobulillar carcinoma representing 15%. Other types are less frequent, representing less than 10% and secondary metastatic breast tumors origins 1 to 2% of all malignant breast tumors. Objective: En this review we show the experience of the Surgery I Service, of the "Hospital Universitario de Caracas" in a 5 years period, involving malignant and infrequent breast tumors. Results: We found in our review, two representatives cases.
The first one is a metastatic breast carcinoid neuroendocrine tumor, which was treated with subtotal mastectomy, and the second one, a metastatic malignant peripheral sheath tumor which was treated with a simple mastectomy. Conclusion: Both of them needed complex surgical and medical treatments to treat both the primary tumor and the metastasis.

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